Monthly Archives: August 2017

CEO of Seattle Genetics, Dr. Clay Siegall’s History, Vision and Passion

Seattle Genetics which started off as a simple and relatively small startup with just a handful of researchers has grown into a more notable establishment and key adversary in the cancer research field. The reason for Seattle Genetics success is its CEO and head of the firm, Dr. Clay Siegall which has a B.S. in zoology from The University of Maryland and a Ph.D in genetics from George Washington University.

Dr. Siegall since establishing his Seattle-based biotech firm has led to creating the first FDA-approved antibody drug conjugate as well as developing more than 20 different drugs while maintaining and embroiling clever business partnerships with other drug manufacturers such as Bayer, Genentech, Pfizer etc.

In a recent interview conducted by Inspirery, Dr. Siegall was asked a few questions regarding his business, financial gains, personal history and experience and his ventures into the capitalist jungle and the medical world.

When asked about how he started his business, Dr. Clay Siegall noted that the question was far broader but decided to mention his personal interest in medicine and humanity’s overall battle against the disease. He decided to specialize in cancer treatment when a faulty chemotherapy treatment worsened the medical condition of a family member. From that experience, he becomes more painstakingly aware of the other available treatments where some were even worse.

When asked how he made money he first stated the most obvious – selling his companies’ proprietary drugs, noting that his company’s antibody drug conjugate is actually the first ever to be approved by the FDA. The other sources of financial gains, he says, are the productive partnerships and the development of technology or certain processes. He also mentioned the risk that goes into being approved by the FDA and the large sums of money needed to do so.

Seattle Genetics become profitable after ten years while being able to overcome certain financial depletion in 1999 and 2000 that being by hard work and proper leadership. With the addition of certain talented salespeople in the early 2000’s and the creation of unique products capital began to arise and profit began to climb upwards.

 

Innovative Approach To Treatment of Rare Diseases

Exciting new innovations in medicine have opened up new treatment options for those who suffer from rare and orphan diseases. Amicus Therapeutics is a biopharmaceutical company that is pushing the boundaries in terms of treatment approaches for rare diseases. They are focused on a group of diseases called Lysosomal Storage Disorders.

 

The treatment options they are researching and developing include chaperone-advanced replacement therapy and enzyme replacement therapy (YourBeautyCraze). The researchers and scientists of Amicus Therapeutics have several treatment methods in focus. One of these includes a drug called migalistat, which is currently in late-stage development. It is designed to treat people with Fabry disease.

 

All of the work that Amicus Therapeutics does is aimed at changing the lives of those they treat. The rare and orphan diseases that this company focuses on affect people across the globe and these people have had to struggle with diseases that are rare and debilitating.

 

The treatment options for these diseases have been limited, and Amicus Therapeutics aims to change that with cutting edge biomedical innovations. The philosophy of the company is to not be limited by prior beliefs and thoughts about what is possible. They continuously push the boundaries and try new techniques. This philosophy has allowed them to be leaders in the treatment of rare and orphan diseases world wide.

 

Amicus Therapeutics has headquarters in New Jersey, USA, and also has a branch in California, USA (Google Finance). They do not manufacture their own drugs but instead work on a contract basis with off site manufactures. The resources of this biopharmaceutical company are focused on research, innovation, design, and working with patients and families.

 

Over the past ten years, this innovative company has received recognition from prominent funds such as the Micheal J. Fox Foundation and the Alzheimers Drug Discovery Foundation. This support has gone towards research efforts in partnership with various medical schools.

 

In addition to this funding, the company has grown due to acquisitions of other groups that were also studying rare diseases. For example, the acquired a company that had been studying enzyme replacement therapy for treating Pompe disease. This acquisition, in turn, boosted Amicus Therapeutics own knowledge regarding Pompe diseases and allowed them to better help their clients who suffer from this ailment (https://www.glassdoor.com/Reviews/Amicus-Therapeutics-Reviews-E26068.htm).

 

The Truth About Arthritis And The Best Medical Practice For Excellent Treatment Options

Arthritis is a common condition affecting aging people but is also a threat to people who have excessive weight, gave a gene history of the illness or suffered physical injury in the past. It is commonly misunderstood to be an illness but it is medically described as a condition caused by degeneration of the cartilage leading to friction between bones. The lack of soft tissue between causes the friction and leads to progressively increasing pain due to movement of joints.

 

Dr. Mathew CiRullo of Family Medicine stated that as joints lose their strength, one is bound to find even the slightest movement unbearable. Another common symptom experienced by arthritis patients is stiffness of joints. Arthritis does not have a medical cure but it has innumerable control measures that lessen the pain and stiffness. The remedies are simple routines that can be easily incorporated into the daily activities such as exercise, medical solutions, and dietary changes.

The easiest remedies are most effectual for arthritis cases that have not advanced too far. Mixing the movements is also essential to prevent long term stiffness. Some safe practices include cycling, walking, swimming, progressive weight lifting, and aerobics. Gentle exercises and stretching moves will get the joint juices in motion. Shifting the sitting position while watching or reading will ensure that motion between joints stays smooth (LongIslandRelief). Reducing excessive weight can drastically reduce the damage of joints due to stress. While the routines are easy, one has to pace the exercises so as not to create unnecessary tension.

 

Medical options to manage arthritis are available from almost any general medical practice in the States. However, there are a few specialized centers that have a specialization in the condition and are therefore better equipped to cater to patients. One revered practice is the Osteo Relief Institute in New Jersey.

 

Osteo Relief Institute offers a wide range of options to manage arthritis and highly qualified professionals to guide patients to undertake the most suitable customized solution. Some common solutions available include topical analgesics, acetaminophen, and technological interventions. The practice uses modern up-to-date tech that offers noiseless and painless scanning and treatment experiences.

More about Osteo Relief Institute at http://releasefact.com/2017/08/the-osteo-relief-institute-provides-more-solutions-for-managing-osteoarthritis-joint-pain/

Canadian Brewing – Not Just For Canadians Anymore

Whether you are looking for a brew for your next barbecue, or for game night, you can’t go wrong with Canadian Beer. These brews are getting the well known recognition they deserve, and making Canadian beer the go to beverage of choice in Canada and the United States.

 

From Surrey, British Columbia, Central City Brewing company has Red Racer Pale Ale, that is known to have a hint of red grapefruit. It’s bitter taste comes from great hops from Yakima, Washington, added to keep the beer fresh tasting and Mariss Otter barley from England.

 

If you are looking for a Gluten Free option, look no further than Glutenberg Belgian Double from Brasseurs Sans Gluten. All of their brews are gluten free and contain grains such as millet to adhere to the strict gluten free guidelines.

 

Steamworks Brewing Company which is located in Vancouver, British Columbia and was founded July 16th, 1995, is very distinct because it uses a central district steam system to power the brewing kettle equipment. Steamworks manufacturers Pilsners, Pale Ales as well as free style brews such as Killer Cucumber Ale. Leading the Steamworks brewery is CEO, Eli Gershkovitch.

 

Eli Gershkovitch is an accomplished brewing executive who has 21 years experience in the brewing industry. He provides leadership for the continued development of cutting edge brewery techniques and formulas that will take Steamworks to the top of the Canadian brewery list. At Steamworks, Eli Gershkovitch knows that having the only steam generated brewery there is no limit to the number of brews and flavors they can come up with.

 

Eli Gershkovitch is proud to announce an addition of a fresh hopped IPA, using fresh hops grown in Vancouver, where they will harvest the hops and immediately brew a fresh cold-brew hopped IPA (Westender). Also coming this winter, they will be developing a white stout for the winter months.

 

Eli Gershkovitch has a saying “You grow to meet demand or demand will shrink to meet you“. And the world needs to watch Steamworks meet those demands.

Glen Wakeman Executive Professional

Glen Wakeman is the CEO and Co-Founder of LaunchPad Holdings, LLC, which is a company that offers software to help budding entrepreneurs build and organize their business plans. The software is full of helpful information and connections to advisers along the way.

Glen Wakeman also holds an advisory role at Nova Four, a company he founded that helps businesses by giving them capital and advice to help them grow. There he mentors CEOs and helps them achieve their business goals.

Glen Wakeman also spent over twenty years at GE, progressively taking on more and more leadership roles that found him working in the United States and abroad. Because of his roles with GE and all the successes that he found while working there, Glen Wakeman was recognized by GE’s Board of Directors as a Growth Leadership role model.

Glen Wakeman believes in five key dimensions of performance: Leadership, Human Capital, Execution, Risk Management and Governance (https://affiliatedork.com/glen-wakeman-inspires-entrepreneurs). His current business and his previous businesses and leadership roles show that he is passionate about quality companies and strengthening individuals in order to achieve business success.

Studying at the University of Scranton, Glen Wakeman received his Bachelor of Science degree in Economics and Finance. He received his MBA in Finance from the University of Chicago.

Writing blog posts about his passions, Glen Wakeman continues to stay connected to individuals on an international level. He is often writing about international finance, global affairs, strategy, raising capital and other topics surrounding business, finance and entrepreneurship. He also mentors executives and shares his extensive knowledge of business, start ups and growing individuals at companies to help the business overall.

With an impressive resume and experience in the fields of finance and business, Glen Wakeman is a global leader in his field and continues to offer advice through his blog and mentor-ship programs.

More about Glen Wakeman at DailyForexReport

The Increase in Home Improvement Concepts

The home improvement market is changing all the time. There are a ton of people that are interested in social media and the evolution of shows that teach people how to make improvements in social media. Many people have been able to see the shows that give people a plethora of ideas. Shows like “Fixer Upper” and “Flip or Flop” have become favorites for all of those homeowners that are looking for ways to accentuate the look and feel of a home.

There is a lot to say for the home improvement shows because it actually increases the amount of home improvement spending in the stores like Home Depot and Rooms-To-Go. People like to accessorize. They like to get a feel for ways to change the structure of the home because they can bring in more space. People can also redesign things inside of the home.

The home improvement concept is changing in a huge way because there are so many people are able to actually able to see exactly how things are being done. There are so many people that are looking for a chance to change things on their own. Most people do not have the ability to hire someone to do the work. That is why more people are going to be able to improve upon their homes when they see the shows.

Home improvement has certainly become a topic that people like to discuss because homeowners like to move from one place to another. There are a lot of people that are interested in totally restructuring their homes. The home improvement shows that have become so popular have given people a chance to really improve upon their homes. So many people are able to build more curb appeal for the home when they watch these shows.

The Impulsive History of James Larkin

James Larkin is best known for being an organizer and labor activist who founded General Workers’ Union and the Irish Transport. The former became largest union of the region after the collapse of the ITGWU.

Larkin was born in Liverpool, England in 1876 and grew up in the area’s slums. As a result, he had very little formal education. However, he worked very hard to contribute to his family’s income and was eventually promoted to foreman at Liverpool’s docks. He was also a political socialist and Marxist from a very young age believing that workers tended to be treated unfairly.

By the time he was 30, he joined and became a full-time organizer for the National Union of Dock Laborers (NUDL). However, his tendency to lean to militant ways made the NUDL very nervous. As a result, he was transported to Dublin, at which time he founded the General Workers’ Union.

The main mission of the General Workers’ Union was to combine all skilled and unskilled Irish industrial workers alike instead of being discriminative between the two. At that time, only 10 percent or less of the total industrial employees of Ireland were unionized.

He also founded the Irish Labor Party, which led to a series of strikes, the most well-known one being the Irish Lockout. In the Irish Lockout, over 100,000 employees went on strike for eight months until fair employment was won.

Jim Larkin is also known for the anti-war demonstrations that he led during the outbreak of the First World War. At that time, he traveled to the U.S. in an attempt to raise funds to fight against the British. However, it is also believed that he was trying to become a globe-trotting public speaker.

However, he was never one to think things through and didn’t plan it very carefully. As a result, he ended up being legally accused of communism and criminal anarchy in 1920 and imprisoned at Sing Sing for three years.

Following that, he was pardoned and deported back to Ireland. After going back to Ireland, he established the Workers’ Union Ireland and won recognition from Communist International in 1924.

Larkin wed Elizabeth Brown in 1903 and they had four sons. She and the two youngest joined him in Chicago in 1914. However, Elizabeth wanted a simpler, quieter life and refused to support the campaign to release him from jail in 1922. The two separated with the rumor that the ITGWU President, Tom Foran had caught Elizabeth’s interest.

Larkin was a very clever entrepreneur but, again, was never one to think things through very well. In the end, he lost both his marriage and the General Workers’ Union after venting about his enemies too publicly and too often.

Some Notable Events In Recent Days for Equities First Holdings

With a lot of pressure on big banks to carefully vet and do their due diligence on clients who they loan to, many businesses and wealthy entrepreneurs are looking to alternative sources for loans. One such firm that provides alternative lending and equity capital is Equities First Holdings, an international financing and loan firm that has been in operation since 2002. Founded by Al Christy Jr., a former investment banker and loan officer at Fidelity Investments and Jeff Smith, a former advisor at Goldman Sachs and Lehman Brothers, Equities First has built a great reputation in helping clients receive working capital for their businesses.

So how do the loans offered by Equities First work? Typically clients who have publicly traded stock can borrow against it with Equities First guidance, and it is sometimes referred to as a non-recourse loan. Most of the loans they finance are given at a low fixed interest rate, and Equities First has done a fantastic job with their loan programs in finding borrowers who’ve been able to turn their loans into profitable income. Most of the clients they work with are corporations and individuals who have high compensation and meet the company’s risk requirements. Most of the loans given by Equities First have been paid back and learn more about Equities First Holdings.

Even as recent as this year, Equities First announced the return and then some of shares that were loaned out to Paysafe, an online transactions company that works similarly to PayPal. Paysafe was able to use the millions in shares it had received to expand its operations, and as part of their agreement were able to pay off the loan plus interest to Equities First. Also paying off a securities loan was Angle PLC back in October of 2016, ending what was a 2-year agreement to finance the company and it Website.

More visit: https://www.glassdoor.co.uk/Overview/Working-at-Equities-First-Holdings-EI_IE1401879.11,34.htm

5 Awesome Ideas For Decorating With All White Interiors

You might not be able to imagine an entire room in red or everything in the colour blue, but an all white space seems to be the go-to concept. Not only is it a pleasing colour in several shades (from warm to cold tones), it’s also a neutral palette that goes with anything. If you think your home will look flat and boring with white, you should definitely reconsider with these fantastic tips.

Adding a Crown Moulding

 

 

The presence of crown molding styles is usually overlooked, but once you take it away, the room just seems more bare. In the kitchen, crown mouldings are usually apparent at the tops of cabinets and as a wall accent. When a simple cove crown moulding is the exact same white as the cabinets, this gives the illusion of a smooth flow towards the ceiling.

Another example is a crown moulding that doesn’t extend until the ceiling. By dividing the space between the cabinet crown moulding and wall crown moulding with a different shade of white, this adds a slight depth to your wall of cabinets.

Playing with Materials and Patterns

 

 

When you have a fantastically bright white bathroom space, the presence of a black and white bathtub really takes centre stage. By combining several types of patterns and materials in a space, the effect is greatly enhanced. Using huge slabs of marble on the floor and wall gives the space a smooth finish while smaller tiles are used to create a difference in perception and texture.

Ever fancied a room in a Moroccan or Middle Eastern style? Delicate touches will make all the difference in the form of intricate cut panel inserts on your cabinets and the presence of metal lanterns in a silver finish is a nice touch. By carefully selecting and placing different materials and patterns around the room, you could very well feel like you’re in a house in the Middle East. Any white space will be instantly brighten with such splendid colours and patterns.

Highlighting Whiteness Through Colours

 

 

An all white room is dazzlingly bright and can sometimes come across as faded. By using a key feature such as a giant wall mural or a feature wall, the white tones of the room are able to stand independently without seeming dull. There might only be two dominant colours in a space, but it definitely won’t be boring.

If you’re a fan of more than one colour, there’s no reason not to invest in lots of bright and bold colours. Although the predominant colour is still white, the different types of colours and textures in the space makes all the difference. For all white spaces, you can even present a white key feature by making use of the walls and ceilings of your home.

Creating a Warm and Natural Space

 

 

Although white has a tendency to feel colder, the use of wood flooring in any room will instantly transforms the atmosphere. Coupled with plenty of natural lighting through large pane windows, it’s actually really easy to create a bright and airy space that’s comfortable.

The addition of wood creates a natural feel that instantly warms up a space. Since white is a bright colour, its addition with wood colours balances the overall tone of your home. Instead of a gloomy undertone or an overly bright space, you’ll end up right where you want to be.

 

Creating a Blank Canvas

 

If you have a marvellous outdoor view, it can seem a shame to detract from the natural beauty. With plenty of floor to ceiling glass and a white interior palette, this creates the perfect opportunity to enjoy and marvel at such a beautiful exterior.

An all white living room is another room that can benefit from minimal colours. Through the careful use of materials, colours and patterns, you’ll have enough natural accents in the room to create a highly elegant atmosphere. Add to that a beautiful outdoor view, this picturesque space will be fit for a king.

White really is a wonderful colour that we sometimes take for granted. Through these fantastic concepts, we can see that it the colour white is really versatile and subtle. With just the right dash of colour and materials, you can transform any space into a magazine worthy addition.

 

 

Modern Methods of Harnessing Solar Energy; Find Out About the PV Shutter Panels

Why use Renewable Energy Sources?

Recent statistics indicate that the world is producing extremely high levels of greenhouse gases. This is attributed to the rise in the use of non-renewable energy sources such as coal.

UNEP has recommended the use of renewable energy to mitigate the effects of the greenhouse gases www.ec.europa.eu/eurostats/index.php . One of the energy sources that remain largely unexploited is the solar energy. This is because home owners consider the installation of the solar panels to be expensive.

There is also a high number of individuals who feel that the panels occupy too much roof space making the roof lose its aesthetic purpose. However, researchers have come up with panels that save on the roof space www.diynetwork.com .

Photovoltaic (PV) Solar Shutter

The louver consists of the PV cells embedded on the outer surface of the panel. The cells harness the solar energy and convert it into usable electric power. The electricity can then be used in various energy-dependent activities at home including heating and lighting.

How it Works

PV shutter is installed on the window to trap the solar energy. The harnessed energy is sent to an inverter which converts the energy into AC current. The AC energy can be plugged into any outlet for use.

PV Solar Shutter Efficacy Rate

The technology is highly efficient. A standard panel of 6 by 8 inches has the potential of producing 350 watts/hour. The energy can sufficiently run the house needs such as lighting, heating and support the use of computers and other energy-dependent gadgets.

Benefits of PV Solar Shutter

The beauty of using the PV cells solar panels is that it requires no roofing space. This fact means that the home owners won’t lose the aesthetic value of the roof. Additionally, the PV solar shutter is easy to install and uninstall. They are installed on the window facing the sun rays.

With the traditional roof panels, it was difficult for the renters to install due to restrictions from the landlords. The new technology makes it possible for millions of renters to harness the solar energy. The discovery will contribute significantly to the reduction of pollution.